Calcein Assay License

SOLVO's patented Calcein assay is an indirect inhibitory-type whole cell assay that provides information on any interaction between the ABC transporter and the test drug. The assay monitors the inhibition of the MDR1/P-gp (ABCB1) or MRP1 (ABCC1) mediated efflux of calcein AM by measuring the increased fluorescence of the calcein dye.
Calcein assay is protected by US (US5.872.014, US6.277.655, US6.391.656) and international (e.g. EPO0784699) patents. Licenses for commercial entities for certain in-house uses are available.

License package includes:

• Non-exclusive license for the Calcein assay method for in-house use
• Detailed assay protocol for 96-well plate
• MS Excel file containing worksheets for calculations and data representation
• MDR1 and MRP1 expressing cells frozen in 2 ml cryogenic vials + description of cell lines and protocol for subculturing
• Free technical support via e-mail or phone
• Personal technical support, training or consulting is also available at the customer's expense

Different pricing schemes are available: up-front licensing fee until patent expiry or yearly subscription fees with a minimum purchase of 2 years; worldwide use or use in a limited geographical area.

For scientific background of Calcein assay please click here.

If you have any questions about our Calcein assay license, please contact us: