The Ready-to-use Transfected MDCKII Monolayer

A new ready-to-use concept for your in vitro drug
transport evaluations

SOLVO Biotechnology introduces PreadyPort^TM in collaboration with ADVANCELL

Monolayer assays using transfected MDCKII cells are widely recognized tools to study the interaction of drugs with efflux and/or uptake transporters. The monolayer system is suitable for performing both inhibition and substrate assessments and is often used to model the net transport events of important fluid compartment barriers in the organism that express a specific transporter at a high level (e.g. MDR1/P-gp in the blood-brain-barrier).

PreadyPort^TM Kits contain 24-transwell plates with differentiated MDCKII cells expressing the selected drug transporter. The innovative shipping medium, developed and patented by ADVANCELL, preserves the properties of the barrier throughout transportation, allowing us to provide customers with a robust, ready-to-use drug transport assay kit.

The first member of the PreadyPort^TM series, the PreadyPort^TM-MDR1 Kit is revolutionary in providing a ready-to-use tool for MDCKII-MDR1 monolayer assays. The kit will allow researchers to perform MDR1 interaction studies on monolayers without bothering about cell-line licensing and culturing.

PreadyPort^TM-MDR1 Applications

PreadyPortTM-MDR1 Features	PreadyPortTM Benefits

For detailed information on the PreadyPort^TM-MDR1 Kit and validation data please click here.

We highly recommend reading the Tips for Success guide before the arrival of the ordered PreadyPort^TM Kits.

You can have access to the User's Manual here.

The PreadyPort^TM Kit is available in the following forms: