Organ Based Solutions

SOLVO Organ Based Solutions integrate multiple assay models for the study of the major pharmacological barriers. Our goal is to develop various assays for all of the key transporters of the major pharmacological barriers. Besides simple membrane based assays, cellular systems and monolayer assays SOLVO is continuously expanding its portfolio with more complex ex vivo and in vivo technologies making SOLVO Organ Based Solutions fully comprehensive.

Descriptions of SOLVO Organ Based Solutions include a short scientific overview, the list of available assay systems and suggestions for the possible screening strategies. There can be more strategies for the research of each pharmacological barrier based on the preferred governing principle: cost efficiency, quickness, guidance of regulatory agencies, or the need for step-by-step, in depth analysis.

This page contains information about following topics: Transporter CNS, Intestinal Drug Absorption, Transporter Pharmacokinetics, Transporter Pharmacodynamics, Transporter Reabsorption, In vitro Species differences.