Login: Password: Registration
Language:
EVENTS

ECCP - European Cancer Cluster Partnering, Oslo

Blood-Brain Barrier Transporters Conference, Stockholm

MEDICA 2010, Dusseldorf

LATEST NEWS

Magic number for Rubik Cube - ISSX special offer

Recorded drug transporter webinar could be attended

Drug Transporter webinar will be held on July 20th and 22nd


QUALITY STATEMENT



MRP2 PREDIVEZ Fluorescent Vesicular Transport Assay
2007-08-01

SOLVO Biotechnology is introducing the revolutionary PREDIVEZ Fluorescent Vesicular Transport Assay Kit for MRP2.

The PREDIVEZ Vesicular Transport kit is a simple and powerful tool to investigate drug-transporter interactions. It provides information on any interaction between the ABC transporter and the test drug that would aff ect the transport of the fluorescent reporter substrate.

The Kit not only contains all you need to conduct Vesicular transport assay but also delivers major technical improvements over the currently available conventinal products such as:
• You can avoid the use of radioactive materials and lengthy scintillation counting by using a fluorescent reporter substrate.
• Larger dynamic range
• Easy to use: All solutions and reagents are pre-prepared and included in the Kit for the assay (No scale and no pH setting are required).
• All-in-one: The Kit contains everything you need for the assay; FROM all reagents and solutions (such as vesicular membrane preparation, assay mix, etc.) TO a CD including an electronic data acquisition and evaluation sheet and all relevant documentation.
• Easier automation, Higher Throughput.
• Lower cost for each Data Point generated

SOLVO PREDIVEZ Fluorescent Vesicular Transport Assay Kits are available in 3, 6 and 10 compund sizes for the human MRP2 transporter.

Recommended equipment:
• 96-well filter plates from Millipore (Cat No. MSFB6B) or equivalent
• Filtration manifold from Millipore (Cat No. MSVMHTS00) or equivalent
• Fluorescent plate reader

Coming up:
• ratMrp2 PREDIVEZ (Q4 of 2007)
• MRP3 PREDIVEZ (Q4 of 2007)
• MRP5 PREDIVEZ (Q4 of 2007)
• BSEP PREDIVEZ (Q2 of 2008)
• mouseBsep PREDIVEZ (Q2 of 2008)

Terms and prices are available upon request.

This page contains information about following topics: Preclinical assay, DMPK, Digoxin assessment, Verapamil, Transporter drug-drug interaction, Transporter Oral bioavailability.