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Catalog > Services > Uptake Transporter Assays > Uptake Transporter Assays

Uptake Transporter Assays

Service	Transporter	Technology	Barrier
OAT1 Uptake Transporter Assay	OAT1	Uptake Transporter Assay	Renal Barrier
Oat1 - rat Uptake Transporter Assay	Oat1 - rat	Uptake Transporter Assay	Renal Barrier
Oatp1a1 - Rat Uptake Transporter Assay	Oatp1a1 - rat	Uptake Transporter Assay	Blood-brain-barrier
OATP1B1 Uptake Transporter Assay	OATP1B1	Uptake Transporter Assay	Hepatic Barrier
MATE2-K Uptake Transporter Assay – probe substrate: TEA	MATE2-K	Uptake Transporter Assay	Renal Barrier
MATE2-K Uptake Transporter Assay – probe substrate: metformin	MATE2-K	Uptake Transporter Assay	Renal Barrier
OATP1B3 Uptake Transporter Assay	OATP1B3	Uptake Transporter Assay	Hepatic Barrier
OATP2A1 Uptake Transporter Assay	OATP2A1	Uptake Transporter Assay	Renal Barrier
OATP2B1 Uptake Transporter Assay	OATP2B1	Uptake Transporter Assay	Hepatic Barrier Intestinal Barrier Renal Barrier
OAT3 Uptake Transporter Assay	OAT3	Uptake Transporter Assay	Renal Barrier
OCT1 Uptake Transporter Assay - probe substrate: metformin	OCT1	Uptake Transporter Assay	Hepatic Barrier Intestinal Barrier
OCT1 Uptake Transporter Assay - probe substrate: TEA	OCT1	Uptake Transporter Assay	Hepatic Barrier Intestinal Barrier
OCT2 Uptake Transporter Assay - probe substrate: metformin	OCT2	Uptake Transporter Assay	Renal Barrier
OCT2 Uptake Transporter Assay - probe substrate: TEA	OCT2	Uptake Transporter Assay	Renal Barrier
OCTN1 Uptake Transporter Assay	OCTN1	Uptake Transporter Assay	Renal Barrier
OCTN2 Uptake Transporter Assay	OCTN2	Uptake Transporter Assay	Renal Barrier
HPT1 Uptake Transporter Assay	HPT1	Uptake Transporter Assay	Intestinal Barrier
MATE1 Uptake Transporter Assay	MATE1	Uptake Transporter Assay	Renal Barrier Hepatic Barrier
NTCP Uptake Transporter Assay	NTCP	Uptake Transporter Assay	Hepatic Barrier
Ntcp - Rat Uptake Transporter Assay	Ntcp - rat	Uptake Transporter Assay	Hepatic Barrier
PEPT1 Uptake Transporter Assay	PEPT1	Uptake Transporter Assay	Intestinal Barrier
PEPT2 Uptake Transporter Assay	PEPT2	Uptake Transporter Assay	Renal Barrier Blood-brain-barrier
Octn2-rat Uptake Transporter Assay	Octn2-rat	Uptake Transporter Assay	Renal Barrier Blood-brain-barrier
*OATP1A2 Uptake Transporter Assay	OATP1A2	Uptake Transporter Assay	Hepatic Barrier Blood-brain-barrier Intestinal Barrier Renal Barrier

Description

SOLVO provides two types of uptake transporter studies: inhibition assessment, and substrate assessment. Both are suitable for drug-drug interaction studies: the indirect assays use predefined uptake transporter substrates for this purpose, while the direct assays can be designed to test the drug-drug interaction of the client’s test article with any potential perpetrator compound.

*OATP1A2 uptake transporter assay is currently available on HEK 293 cells transiently transfected with OATP1A2.

Unique services at SOLVO: OCT1, OCT2, and MATE2-K inhibition assessment assays are available for alternative probe substrates; TEA and Metformin as well.

For more information on Uptake Transporter Assays, please click here.

Technology background