Uptake Transporter Assays
Description
SOLVO provides two types of uptake transporter studies: inhibition assessment, and substrate assessment. Both are suitable for drug-drug interaction studies: the indirect assays use predefined uptake transporter substrates for this purpose, while the direct assays can be designed to test the drug-drug interaction of the client’s test article with any potential perpetrator compound.
Unique service at SOLVO: OCT1 and OCT2 inhibition assessment assays are available for alternative probe substrates; TEA and Metformin as well.
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