Senior Principal Research Scientist AbbVie Inc. North Chicago, IL, USA
J. Cory Kalvass, Ph.D., is a Senior Principal Research Scientist in Drug Metabolism and Pharmacokinetics at AbbVie. He received dual bachelor degrees in Biochemistry and Chemistry from the University of Rochester and his Ph.D. in Pharmaceutical Sciences from the School of Pharmacy at the University of North Carolina. He has 18 years experience as an ADME / PK/PD scientist in drug discovery, working at Pfizer, Eli Lilly and AbbVie. Dr. Kalvass’ research interests include the study of CNS drug penetration and action, including transporter kinetics, as well as applying PK/PD approaches for establishing in-vitro-to-in-vivo and preclinical-to-clinical correlations. He is a champion of “free drug hypothesis” and has refined equilibrium dialysis methods to better estimate free drug levels in in vitro incubations, plasma, brain as well as other tissues. He is the author of over 50 peer-reviewed publications and abstracts. Dr. Kalvass is recipient of a number of awards including 2009 AAPS Meritorious Manuscript Award.