Nancy Kaehr Chair in Research, Professor of Pediatrics, Medicine (Nephrology) Cellular Molecular Medicine University of California San Diego, CS, USA
Sanjay K. Nigam is the Nancy Kaehr Chair in Research and Professor of Pediatrics, Medicine (Nephrology) and Cellular Molecular Medicine at Univ. of California San Diego. He received his MD from the University of Pennsylvania. He conducted his postdoctoral research at the Rockefeller Univ. with Nobel laureate Gunter Blobel. He did his clinical Nephrology fellowship training at Columbia. Prior to moving to UCSD, he was on the faculty of Harvard Medical School and served as Director of Renal Research at Brigham and Women's Hospital. His laboratory discovered the gene now known as OAT1 (originally NKT) as well as a number of other SLC22 transporters. His lab also first described the phenotypes of the OAT1, OAT3 and URAT1 knockout mice from a pharmacological, toxicological and physiological perspective. Extensive metabolomics analyses of these mice, as well as "omics" based metabolic reconstructions, led to the "Remote Sensing and Signaling Hypothesis" (Nature Rev. Drug Disc. 2015).