CACOREADY™

Product Cell Line Transporter Technology Membrane Type Probe Substrate Read Out Reference Inhibitor Positive Control Dynamic Range

Description

CACOREADYTM, is an innovative cell-based and ready-to-use kit. The kit consists of 24 or 96 well insert-integrated plates containing differentiated and polarized Caco-2 barriers. CACOREADYTM allows in vitro intestinal absorption evaluation of drug targets. CACOREADYTM is a flexible technology because plates can be used up to 5 days after ideal cell barrier differentiation. CACOREADYTM is a time and cost-saving tool for early stage drug discovery and development.

SOLVO Biotechnology introduced CACOREADYTM in collaboration with ADVANCELL and ReadyCell (Spain).

Applications

  • Evaluation of oral absorption efficiency, bioavailability and toxicity
  • Study of mechanisms involved in intestinal absorption
  • Study of Drug Transporters and Drug-Drug Interaction
  • Suitable for research on new delivery systems
 
Benefits
  • Available on demand
  • Provided after cell barrier is differentiated reducing the time needed for in house maintenance
  • Flexible as the kit can be applied up to 5 days after delivery
  • Time saving and cost-effective
  • Adaptable to automated procedures, HTS
  • Reproducible
  • Handling is easy and clean
  • Cells preserves their functionality after transportation
  • Shipping medium easy to remove by liquefaction at 37°C
Features
  • 24 and 96-HTS insert- integrated plate format
  • Ready-to-use
  • 24-TranswellTM (Costar) or 96-Multiwell (Millipore) format
  • Exclusive solid shipping medium

 

We highly recommend reading the “Chemicals and instruments needed” and the “Tips for Success guide” before your CACOREADYTM Kits arrive. Please request them from your local account manager

 

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