CACOREADY™

Product Cell Line Transporter Technology Membrane Type Probe Substrate Readout Reference Inhibitor Positive Control Dynamic Range

Description

CACOREADYTM, is an innovative cell-based and ready-to-use kit. The kit consists of 24 or 96 well insert-integrated plates containing differentiated and polarized Caco-2 barriers. CACOREADYTM allows in vitro intestinal absorption evaluation of drug targets. CACOREADYTM is a flexible technology because plates can be used up to 5 days after ideal cell barrier differentiation. CACOREADYTM is a time and cost-saving tool for early stage drug discovery and development. SOLVO Biotechnology introduced CACOREADYTM in collaboration with ReadyCell (Spain). Applications
  • Evaluation of oral absorption efficiency, bioavailability and toxicity
  • Study of mechanisms involved in intestinal absorption
  • Study of Drug Transporters and Drug-Drug Interaction
  • Suitable for research on new delivery systems
Benefits
  • Available on demand
  • Provided after cell barrier is differentiated reducing the time needed for in house maintenance
  • Flexible as the kit can be applied up to 5 days after delivery
  • Time saving and cost-effective
  • Adaptable to automated procedures, HTS
  • Reproducible
  • Handling is easy and clean
  • Cells preserves their functionality after transportation
  • Shipping medium easy to remove by liquefaction at 37°C
Features
  • 24 and 96-HTS insert- integrated plate format
  • Ready-to-use
  • 24-TranswellTM (Costar) or 96-Multiwell (Millipore) format
  • Exclusive solid shipping medium
Please request details from your local account manager.
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