CACOREADY™
Product |
Cell Line |
Transporter |
Technology |
Membrane Type |
Probe Substrate |
Readout |
Reference Inhibitor |
Positive Control |
Dynamic Range |
Shipping Option |
Description
CACOREADY
TM, is an innovative cell-based and ready-to-use kit. The kit consists of 24 or 96 well insert-integrated plates containing differentiated and polarized Caco-2 barriers. CACOREADY
TM allows
in vitro intestinal absorption evaluation of drug targets. CACOREADY
TM is a flexible technology because plates can be used up to 5 days after ideal cell barrier differentiation. CACOREADY
TM is a time and cost-saving tool for early stage drug discovery and development.
SOLVO Biotechnology introduced CACOREADY
TM in collaboration with ReadyCell (Spain).
Applications
- Evaluation of oral absorption efficiency, bioavailability and toxicity
- Study of mechanisms involved in intestinal absorption
- Study of Drug Transporters and Drug-Drug Interaction
- Suitable for research on new delivery systems
Benefits
- Available on demand
- Provided after cell barrier is differentiated reducing the time needed for in house maintenance
- Flexible as the kit can be applied up to 5 days after delivery
- Time saving and cost-effective
- Adaptable to automated procedures, HTS
- Reproducible
- Handling is easy and clean
- Cells preserves their functionality after transportation
- Shipping medium easy to remove by liquefaction at 37°C
Features
- 24 and 96-HTS insert- integrated plate format
- Ready-to-use
- 24-TranswellTM (Costar) or 96-Multiwell (Millipore) format
- Exclusive solid shipping medium
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Please request details from your local account manager.