PREDICELL™ Kits

Product Cell Line Transporter Technology Membrane Type Probe Substrate Read Out Reference Inhibitor Positive Control Dynamic Range
SB-OAT1-PREDICELL™ UT-24w Kit OAT1
Uptake Transporter Assay
SB-OAT1-PREDICELL™ UT-96w Kit OAT1
Uptake Transporter Assay
SB-NTCP-PREDICELL™ UT-24w Kit NTCP
Uptake Transporter Assay
SB-NTCP-PREDICELL™ UT-96w Kit NTCP
Uptake Transporter Assay
SB-OATP1B1-PREDICELL™ UT-24w Kit OATP1B1
Uptake Transporter Assay
SB-OATP1B1-PREDICELL™ UT-96w Kit OATP1B1
Uptake Transporter Assay
SB-OATP1B3-PREDICELL™ UT-24w Kit OATP1B3
Uptake Transporter Assay
SB-OATP1B3-PREDICELL™ UT-96w Kit OATP1B3
Uptake Transporter Assay
SB-OCT2-PREDICELL™ UT-24w Kit OCT2
Uptake Transporter Assay
SB-OCT2-PREDICELL™ UT-96w Kit OCT2
Uptake Transporter Assay
SB-MATE1-PREDICELL™ UT-24w Kit MATE1
Uptake Transporter Assay
SB-MATE1-PREDICELL™ UT-96w Kit MATE1
Uptake Transporter Assay
SB-MATE2-K-PREDICELL™ UT-24w Kit MATE2
Uptake Transporter Assay
SB-MATE2-K-PREDICELL™ UT-96w Kit MATE2
Uptake Transporter Assay
SB-OAT3-PREDICELL™ UT-96w Kit OAT3
Uptake Transporter Assay
SB-OCT1-PREDICELL™ UT-24w Kit OCT1
Uptake Transporter Assay
SB-OCT1-PREDICELL™ UT-96w Kit OCT1
Uptake Transporter Assay
SB-OCTN1-PREDICELL™ UT-24w Kit OCTN1
Uptake Transporter Assay
SB-OCTN1-PREDICELL™ UT-96w Kit OCTN1
Uptake Transporter Assay
SB-OCTN2-PREDICELL™ UT-24w Kit OCTN2
Uptake Transporter Assay
SB-OCTN2-PREDICELL™ UT-96w Kit OCTN2
Uptake Transporter Assay
SB-ASBT-PREDICELL™ UT-24w Kit ASBT
Uptake Transporter Assay
SB-ASBT-PREDICELL™ UT-96w Kit ASBT
Uptake Transporter Assay
SB-OATP1A2-PREDICELL™ UT-24w Kit OATP1A2
Uptake Transporter Assay
SB-OATP1A2-PREDICELL™ UT-96w Kit OATP1A2
Uptake Transporter Assay
SB-OATP2B1-PREDICELL™ UT-24w Kit OATP2B1
Uptake Transporter Assay
SB-OATP2B1-PREDICELL™ UT-96w Kit OATP2B1
Uptake Transporter Assay

Description

PREDICELLTM, the world’s first commercially available ready-to-use uptake transporter assay kits for the following transporters:
ASBT
MATE1
MATE2K
NTCP
OAT1
OAT3
OATP1B1
OATP1B3
OATP2B1
OATP1A2
OCT1
OCT2
OCTN1
OCTN2


PREDICELLTM kits enable interaction studies with drug uptake transporters. The kits contain transfected as well as parental control cells on tissue culture plates. Transporter interactions are detected through changes in accumulation inside the cells.

The assays are available as:

  • 96-well kit for inhibition studies
  • 24-well kit for direct uptake studies (substrate assessment)

Benefits

With the PREDICELLTM Kits SOLVO aims to provide access to uptake transporters

  • if you prefer in-house studies
  • if you do not have cell culturing capacities
  • if you do not plan to acquire or develop cell lines

In the box

  • Plates with cells
  • User’s Manual with sample transport assay protocol
  • Product data sheet
  • Optional reagents
  • Thermal and mechanical insulation

Additional reagents to conduct a study straight out of the box can be included upon request..

How to perform uptake assay with ready to use PREDICELL kit? Watch our PREDICELLTM video in the Download Center! - Click here!

Technical aspects

Standard timeline comprises seeding on Monday, Kit assembly and dispatch on Tuesday and delivery on Wednesday or Thursday (depending on your location). Studies may be conducted within 24 hours upon delivery. Alternative schedules are possible upon request.

One 30x30x40 cm box contains up to five plates, documentation and optional reagents.

During shipment, the activity of uptake transporters in the PREDICELLTM Kit remains stable during shipment for 48 hours, as shown in Figure 1.


Figure 1.: Testing insulation capabilities of the packaging in a 4°C refrigerator.  Estrone-3-sulfate uptake activity of OATP1B1 trasfected cells and TEA uptake activity of OCT1 cells were tested on packaged cells put into the refrigerator as well as control cells kept in incubator.

Learn more about the scientific background of the uptake transporter assay technology.

 

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