|Service||Cell Line||Transporter||Technology||Membrane Type||Probe Substrate||Read Out||Reference Inhibitor||Positive Control||Dynamic Range|
|Hepatocyte Uptake Assay||Hepatocyte Uptake Assay
The SOLVO hepatocyte uptake assays are available using commercially available hepatocytes from human, rat or other species. The main purpose of this assay is to evaluate whether Test Articles (TAs) are actively (through a transporter) or passively (by diffusion) taken up into hepatocytes. Data from the assay can help scientists with Test Articles in different stages of development:
SOLVO uses the gold-standard oil-spin method to evaluated active uptake of a compound in hepatocytes. In addition, it is also possible to use plateable cells, to run the assay
Learn more about the Technology background of the Hepatocyte Uptake Assay.