SOLVO Biotechnology (SOLVO) and Austrian Institute of Technology (AIT ), Austria, have established a strategic partnership with the goal to offer Preclinical and Clinical Molecular Imaging Services and a wide portfolio of related Services, including transporter-specific microPET-MRI.
Positron emission tomography (PET) is a functional imaging modality at molecular level and provides valuable insights into biochemical, physiological, pathological or pharmacological processes in vivo. Small amounts of biologically active compounds are labelled with positron emitting radionuclides (11C, 18F, 68Ga, 124I) and then administered to the subjects. The temporal and spatial distribution of these PET tracers within the body is measured with PET. microPET offers the unique opportunity to image small animal models of diseases, including genetically engineered animals. Data can be obtained non-invasively, repeatedly, and quantitatively from the same animal. Current applications include a diverse field comprising metabolism and substrate utilization in various vital organs such as the heart and brain, neurotransmitters, receptors and transporter proteins, as well as in elucidating tumor biology, for instance, angiogenesis, hypoxia and apoptosis. In recent research efforts, microPET has found application in a wide area ranging from basic insights into normal physiology and disease processes to drug development and early response to anticancer and gene therapy.