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Posters

  1. In vitro tools to investigate creatine transport inhibition
  2. A systematic in vitro investigation of the inhibitor preincubation effect on multiple classes of clinically relevant transporters*
  3. Ortholog identification of human, monkey and rat members of the OATP1 family in the liver
  4. Characterization of the specific interaction between BCRP (ABCG2/MXR) transporter and tolcapone
  5. Searching for specific and clinically relevant BCRP (ABCG2) probe
  6. In vitro evaluation of OATP1B1- and OATP1B3-mediated drug-drug interactions using statins as probe substrates
  7. Evaluation of Dabigatran etexilate as a potential new in vitro P-gp substrate
  8. Complementary in vitro tools to investigate renal drug transport
  9. Comparison of Inhibition Potency of Thirty-one Marketed Drugs Towards BSEP in Insect (Sf9) vs. Mammalian Based (HEK293) Cell Vesicles
  10. Comparative study of enzyme kinetic parameters in different expression systems using relevant BCRP (ABCG2) probe substrates
  11. A Proximate™ as a novel predictive model of polymyxin B and gentamicin induced nephrotoxicity
  12. Assay calibration to refine prediction of P-gp mediated DDI based on in vitro vesicular transport assay data
  13. Adaptation of microdialysis techniques to study brain penetration of drugs and substrate-inhibitor interactions of ABC transporters at the BBB in mice
  14. Seliciclib(R-Roscovitine) is a selective ABCB1 substrate
  15. Multidrug resistance testing with in vitro ABC transporter assay
  16. Development of High-throughput Human OCT2 Expressing Uptake Assay System
  17. Mouse Bsep ATPase assay - a non-radioactive tool for assessment of the cholestatic potential of drug
  18. MRP2-mediated E217βG transport potentiation: in vitro - in vivo correlation and species specificity
  19. Kinetic characterization of sulfasalazine transport by ABCG2
  20. Passive permeability is a crucial parameter in choosing the right assay to detect the interaction of compounds with ABCB1 (Pgp) and ABCG2 (BCRP)
  21. Comparison of cell based and membrane based high throughput assays for the detection of drugs interacting with the BCRP transporter
  22. Comparative Analysis of Human Multidrug Resistance-Associated Protein 2 (MRP2) and Rat Mrp2
  23. Characterization of the interactions between BCRP (ABCG2/MXR) transporter and DMARDs; sulfasalazine, leflunomide and methotrexate
  24. Excipients may modulate the pathways in ADME/Tox via ABC-transporters
  25. Carry and Cramp - Cyclodextrins with dual function
  26. Interaction of quercetin and its metabolites with the transporter ABCC2 (cMOAT, MRP2)
  27. Chloroacetanilide herbicides and their metabolites interact with human Efflux Transporters and modulate drug absorption
  28. Interaction of Pesticides with human Efflux Transporters
  29. Laboratory validation and multicenter performance evaluation of the Solvo MDQ-Kit
  30. Multicenter performance evaluation of the MultiDrugQuant assay kit
  31. Membrane transporters as determinants ofADMETox (AbsorptionMetabolism-Excretion-Toxicity) properties ofdrugs and environmental toxicants
  32. Chlorothiazide is an OAT1, OAT3 and BCRP substrate - implications in renal secretion of chlorothiazide
  33. Effect of PSC-833 (Valspodar) on the intestinal absorption of digoxin in mouse and rat, using different in vivo and ex vivo methods
  34. Revised approach in assessing Bsep-Cyclosporin A interactions in bile duct cannulated rats
  35. Optimization of cellular uptake assays for the determination of test compound interactions with OAT1 (SLC22A6)
  36. Chlorothiazide is a substrate for the human uptake transporters OAT1 and OAT3