Uptake Transporter Services

SOLVO provides two types of uptake transporter studies: inhibition assessment, and substrate assessment. Both are suitable for drug-drug interaction studies: the inhibition assays use predefined uptake transporter substrates for this purpose, while the substrate assays can be designed to test the drug-drug interaction of the test compound with any potential perpetrator compound.

The inhibition and substrate uptake transporter assays are performed with stable cell lines expressing selected human or rat uptake transporters.