Services

Efflux Transporter Services

• ATPase Assays
• Vesicular Transport Assays
• Dye Efflux Assays
• MDCKII Monolayer Assays
• Caco-2 Transporter Knockout Cell-Based Assays
• LLC-PK1 Monolayer Assays

Uptake Transporter Services

SOLVO Biotechnology utilizes a wide range of stably transfected cell lines for studying the interaction of test articles with uptake transporters.

• Uptake Transporter Assays

B-Clear® assays

• Sandwich-cultured hepatocyte Assay

Proximal Tubule Cell monolayer assays

• Renal Proximal Tubule Cell Monolayer Assay

Caco-2 Services

• Caco-2 Monolayer Assay
• Caco-2 Transporter Knockout Cell-Based Assays

LC/MS-MS Quantification of Transporter Proteins

SOLVO Biotechnology offers“LC/MS-MS Quantification of Transporter Proteins”

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In Vivo ADME Services

• Biliary Excretion - rat
• Brain Microdialysis (MD) - mouse, rat
• Molecular Imaging – Preclinical and Clinical PET

Hepatocyte uptake assays

• Hepatocyte Uptake Assay

Drug Metabolism Services

• Metabolic profile and identification
• Metabolic stability

Other Services

• Rat Brain Endothelial Cell Monolayer Assay
• Excipients and Absorption Service
• LC/MS-MS Quantification of Transporter Proteins