Vesicular Transport Membranes

Product Cell Line Transporter Technology Membrane Type Probe Substrate Read Out Reference Inhibitor Positive Control Dynamic Range
SB BCRP HEK293 Membrane BCRP
Vesicular Transport Assay
HEK293 E3S >10
SB BCRP Sf9 HAM Membrane BCRP
Vesicular Transport Assay
Sf9-HAM E3S >5
SB BCRP M Membrane BCRP
Vesicular Transport Assay
MCF7 E3S >5
SB cyBcrp HEK293 Membrane Bcrp - cynomolgus monkey
HEK293 E3S >5
SB BSEP HEK293 Membrane BSEP
Vesicular Transport Assay
HEK293 Taurocholate >5
SB BSEP Sf9 Membrane BSEP
Vesicular Transport Assay
Sf9 Taurocholate >5
SB BSEP Hi5 Membrane BSEP
Vesicular Transport Assay
Hi5 Taurocholate >5
SB mouseBsep Sf9 Membrane Bsep - mouse
Vesicular Transport Assay
Sf9 Taurocholate >5
SB ratBsep HEK293 Membrane Bsep - rat
Vesicular Transport Assay
HEK293 Taurocholate >5
SB MDR1/P-gp K Membrane MDR1/P-gp
Vesicular Transport Assay
K N-Methyl Quinidine >5
SB MDR1 HEK293 Membrane MDR1/P-gp
Vesicular Transport Assay
HEK293 N-Methyl Quinidine >5
SB cyMdr1 HEK293 Membrane Mdr1 - cynomolgus monkey
HEK293 NMQ >5
SB mouseMdr1a HEK293 Membrane Mdr1a - mouse
Vesicular Transport Assay
HEK293 N-Methyl Quinidine >5
SB ratMdr1b Sf9 HAM Membrane Mdr1b - rat
Vesicular Transport Assay
Sf9-HAM N-Methyl Quinidine >5
SB MRP1 Sf9 Membrane MRP1
Vesicular Transport Assay
Sf9 LTC4 >5
SB MRP2 Sf9 Membrane MRP2
Vesicular Transport Assay
Sf9 E217ßG >5
SB MRP2 HEK293 Membrane MRP2
Vesicular Transport Assay
HEK293 E217ßG >5
SB MRP3 Sf9 Membrane MRP3
Vesicular Transport Assay
Sf9 E217ßG >3
SB MRP3 HEK293 Membrane MRP3
Vesicular Transport Assay
HEK293 E217ßG >5
SB MRP4 HEK293 Membrane MRP4
Vesicular Transport Assay
HEK293 DHEAS >5
SB MRP5 HEK293 Membrane MRP5
Vesicular Transport Assay
HEK293 CDCF >3
SB ratMrp2 HEK293 Membrane Mrp2 - rat
Vesicular Transport Assay
HEK293 E217ßG >5
SB ratMrp3 HEK293 Membrane Mrp3 - rat
Vesicular Transport Assay
HEK293 E217ßG >5

Description

Membrane Preparations for Vesicular Transport Assays (VT) are suitable for general drug-efflux transporter interaction studies. Both substrate and inhibitor interactions can be assessed using vesicles. The success of substrate interaction studies strongly depends on the passive permeability of the compound. High permeability substrates might not be detected.

Control Membranes with no-, or significantly lower transporter activity are also available.

For the scientific background of our vesicular transport assays, please click here.

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